Rheumatoid arthritis

Autoimmune diseases such as MS and rheumatoid arthritis affect almost four percent of the global population. A new study has now identified a naturally occurring compound that may provide a new way of treating these debilitating diseases.

Instead of injections or pills, why not engineer bacteria to secrete therapeutic molecules from within our gut? A new study is showing how a genetically modified probiotic can produce an anti-inflammatory molecule to treat rheumatoid arthritis in rats.

Immune suppression can help relieve symptoms of autoimmune diseases, but it can cause complications. A new nanoparticle therapy selectively targets problematic immune cells, and was able to significantly delay and even prevent arthritis in mice.

A new study has provided more evidence gut bacteria plays a role in the development of rheumatoid arthritis. The research suggests an abnormal immune response to a common species of gut bacteria could influence the development of the disease.

Scientists studying the activity of a drug used to treat rheumatoid arthritis have discovered some surprising metabolic functions, some of which may be useful when it comes to countering diabetes and obesity.

A research team has discovered a novel mechanism in which a key protein drives the inflammatory damage associated with rheumatoid arthritis. The foundational finding could lead to entirely new pathways to treat this autoimmune disease affecting millions.

Positive Phase 3 trial results for a new antibody treatment targeting rheumatoid arthritis have recently been reported. The therapy is hoped to offer a new option to patients struggling with current treatments and should be available within the next year.

A new study from scientists in Japan and the US has identified a form of inter-neuron communication as a key mechanism in the way inflammation spreads between joints in conditions like rheumatoid arthritis.

A new discovery around inflammation and excessive cell death in the body illuminates the key role a certain enzyme plays in the process, and how targeting a "sugar tag" could lead to treatments for a wide range of conditions.

By tapping into the unique immune system of alpacas and special nanobodies they produce, scientists have developed a promising technique for tempering chronic inflammation associated with conditions such as arthritis.

Impressive research is suggesting bacterial imbalances in the gut microbiome may play a major role in the development of rheumatoid arthritis. The preclinical study found damage to the gut lining directly correlates with joint inflammation and severity.

Researchers at Washington University have tested an experimental new treatment for rheumatoid arthritis in mice. The team implanted stem cells that have been reprogrammed to secrete anti-inflammatory drugs only when they sense inflammation.