Rheumatoid arthritis
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Autoimmune diseases such as MS and rheumatoid arthritis affect almost four percent of the global population. A new study has now identified a naturally occurring compound that may provide a new way of treating these debilitating diseases.
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Instead of injections or pills, why not engineer bacteria to secrete therapeutic molecules from within our gut? A new study is showing how a genetically modified probiotic can produce an anti-inflammatory molecule to treat rheumatoid arthritis in rats.
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Immune suppression can help relieve symptoms of autoimmune diseases, but it can cause complications. A new nanoparticle therapy selectively targets problematic immune cells, and was able to significantly delay and even prevent arthritis in mice.
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A new study has provided more evidence gut bacteria plays a role in the development of rheumatoid arthritis. The research suggests an abnormal immune response to a common species of gut bacteria could influence the development of the disease.
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Scientists studying the activity of a drug used to treat rheumatoid arthritis have discovered some surprising metabolic functions, some of which may be useful when it comes to countering diabetes and obesity.
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A research team has discovered a novel mechanism in which a key protein drives the inflammatory damage associated with rheumatoid arthritis. The foundational finding could lead to entirely new pathways to treat this autoimmune disease affecting millions.
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Positive Phase 3 trial results for a new antibody treatment targeting rheumatoid arthritis have recently been reported. The therapy is hoped to offer a new option to patients struggling with current treatments and should be available within the next year.
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A new study from scientists in Japan and the US has identified a form of inter-neuron communication as a key mechanism in the way inflammation spreads between joints in conditions like rheumatoid arthritis.
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A new discovery around inflammation and excessive cell death in the body illuminates the key role a certain enzyme plays in the process, and how targeting a "sugar tag" could lead to treatments for a wide range of conditions.
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By tapping into the unique immune system of alpacas and special nanobodies they produce, scientists have developed a promising technique for tempering chronic inflammation associated with conditions such as arthritis.
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Impressive research is suggesting bacterial imbalances in the gut microbiome may play a major role in the development of rheumatoid arthritis. The preclinical study found damage to the gut lining directly correlates with joint inflammation and severity.
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Researchers at Washington University have tested an experimental new treatment for rheumatoid arthritis in mice. The team implanted stem cells that have been reprogrammed to secrete anti-inflammatory drugs only when they sense inflammation.
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