Vaccines
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A new vaccine targeting the three most common human fungal infections is showing promising results in early preclinical studies. The data paves the way for future human trials in the hopes of preventing infections linked to over one million deaths a year.
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Promising results have been published from the first human trial testing an experimental vaccine targeting the deadly Marburg virus. Flagged as a potential pandemic-causing virus, this is the first Marburg vaccine to move into Phase 2 human trials.
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In a blow to researchers across the world, the only HIV vaccine currently in Phase 3 human trials has been deemed a failure. The experimental vaccine's failure turns the current research focus onto several other candidates only in early-stage human trials.
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Moderna has announced promising results from its Phase 3 trial testing an mRNA vaccine for RSV in older adults. Data indicates the vaccine is nearly 84% effective at preventing moderate disease and the company expects to file for FDA approval this year.
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The US Department of Agriculture (USDA) has approved the world's first insect vaccine, developed to protect honeybees from a devastating bacterial disease known to decimate entire hives.
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Scientists have found a way to fight cancer with cancer, by genetically engineering cancer cells to release drugs at established tumor sites and stimulating the immune system. Tests in mice showed promise as both a therapy and preventative vaccine.
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It's often hard to see the forest from the trees but if we zoom out a little it becomes clear 2022 saw some incredible breakthroughs in the world of medical science. All of these stories are landmark moments that are set to shape the future of medicine.
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The first results from a trial testing mRNA technology against cancer reveal 44% of patients fared better than those on conventional treatments. The announcement from Moderna reveals Phase 3 trials for its mRNA skin cancer vaccine will commence next year.
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An incredible study presents an mRNA vaccine that can provide protection from all 20 known influenza A and B virus subtypes. It's hoped the vaccine would prevent future flu pandemics by promoting immunity against strains yet to cross over from animals.
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Even when someone is determined to beat their fentanyl addiction, there's still a good chance they will relapse at some point, and start taking the opioid again. A new vaccine is designed to help get them back on track, by blocking fentanyl's effect on the brain.
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A new paper in the journal JAMA Oncology has reported the results of a decade-long Phase 1 human trial testing an experimental breast cancer vaccine. The treatment was found to be "very safe" and a large Phase 2 trial is now underway testing efficacy.
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An ounce of prevention is worth a pound of cure, so they say. Scientists have now demonstrated a new potential cancer vaccine that involves injections of dormant tumor cells to stimulate the immune system and help prevent the onset of cancer.
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