Brigham and Women’s Hospital

Researchers have gained new insights into largely overlooked circular RNAs in brain cells and the crucial role they play in diseases like Alzheimer’s and Parkinson’s, opening the door to developing diagnostic tests and treatments for them.

Researchers have found that an intranasal drug, currently being tested as an MS treatment, reduced brain inflammation and improved cognition in mice with Alzheimer’s disease, independent of the amount of beta-amyloid plaques present.

Not only are colonoscopies invasive and uncomfortable, they may also miss gut-problem-related biomarkers that are only present in the body for a short time. A new "smart pill" is designed to address such shortcomings, using live light-up bacteria.

Scientists have demonstrated in mice that specially designed probiotics can reduce brain inflammation from diseases like multiple sclerosis. The study points to new potential therapies for chronic conditions that may be as simple as popping a pill.

We all know fruit and vegetables are good for our overall health. But in a first-of-its-kind multi-year study, researchers have shown that flavanols found in these foods are tied to brain function, and a deficiency may drive age-related memory loss.

Surgeons have successfully performed a first-of-its-kind procedure in utero to treat a potentially fatal genetic defect in the brain. Usually treated after birth, the new procedure could give newborns a better chance of a normal life.

Even though some conditions cause people to lose their appetite, those folks have to keep eating in order to recover. A new "electroceutical" ingestible capsule could help, by making them feel hungry … and it was inspired by a lizard's skin.

Researchers have developed a platform that allows wireless ingestible devices to be tracked in 3D as they travel through the gut, which may provide a cheaper, less invasive way of investigating disorders that affect gastric motility.

The rise of drug-resistant bacteria calls for new approaches to how doctors protect against bone infection after joint replacements, and a potent new form of bone cement is poised to take up the fight.

A common perception around meal timing and human health is that it’s best to steer clear of late-night dinners and midnight snacking, and a new study has offered some compelling insights into the reasons why.

People subjected to irregular sleeping and eating habits through shift work are known to have higher risk of a wide range of health problems, and a new study has drilled into the impacts of this lifestyle on mental health.

At the heart of much research into Parkinson's, both its causes and new forms of treatment, is a type of brain protein called alpha-synuclein, and new research has found that it appears to be leading a "double life."