Genetics
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In two separate studies, researchers have identified the mutation that can lead to the autoimmune disease lupus. The discovery opens the door to new therapeutic approaches and testing for the mutation, which would ensure early disease diagnosis.
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Throughout 2023, researchers have looked at pain, especially chronic pain, and its molecular mechanisms, in an effort to find new, targeted ways to effectively resolve the complex condition. We present this year’s top discoveries in pain research.
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In a finding that could have a significant impact on personalized medicine, scientists have identified five blood compounds linked to suicidal ideation. It could prove crucial in assessing risk factors and for new targeted treatment of depression.
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It’s a safe assumption that we all know binge-drinking is not good for our general health. But a new study shows that one big alcohol-fueled session a week is significantly more harmful than spreading that same amount of drinks out over seven days.
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Researchers have discovered that mice possess a natural form of gene therapy, a non-coding RNA that can sidestep genetic mutations. They were able to engineer a programmable version that might be used to treat genetic diseases in humans.
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A study has found that an electric eel’s discharge is strong enough to transfer genetic material from the environment into the cells of nearby animals. The finding suggests that electric eels could affect genetic modification in nature.
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In a feat only a few non-human animals have accomplished so far, a common dark-furred mouse has passed what’s known as the mirror self-recognition test. Backed by supporting genetic cues, this suggests mice can actually recognize themselves.
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Researchers have taken the best genetic characteristics of the Fraser fir, arguably the most popular choice for Christmas tree, and used them to create a tree that’s taller, prettier, and – importantly – sheds only a fraction of its needles.
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Research has revealed how genetic changes in a specialized population of brain cells called microglia contribute to neuroinflammation and, in turn, to Alzheimer’s disease. The findings could lead to more effective, targeted therapeutics.
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A new study has identified, for the first time, how the mutated protein p53, present in half of all human cancers, drives tumor growth. The discovery will not only facilitate a rethink of the way cancer is treated but may lead to new therapeutics.
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CRISPR systems are powerful tools for genetic engineering, but they have their limitations. Now, scientists have discovered almost 200 new CRISPR systems in bacteria, and found that some can edit human cells even more precisely than existing ones.
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Up to four million Americans may be enduring this common ailment right now. But what if a microbe found in the gut could relieve it and restore gut health? Scientists believe they've found the genetic key that powers this microbe's motility engines.
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