Inflammatory

A new study claims to explain the association between gum disease and diabetes, cardiovascular disease and even Alzheimer’s. The research demonstrates how periodontitis can initiate a systemic immune response that spreads throughout the entire body.

A study investigating the relationship between the gut microbiome, genetics, and MS, is suggesting bacteria certainly plays a role in modulating the effects of the disease but whether that role is positive or negative may be determined by genetics.

Researchers have found two new biomarkers in sweat that are associated with inflammatory bowel disease, and have produced a prototype wearable device that could track their levels as a way of warning users when flareups are about to occur.

Researchers have uncovered what they say is the first direct evidence to show how an immune response can contribute to Alzheimer’s disease. The study adds to evidence highlighting the role of neuroinflammation in dementia and cognitive decline.

An international team of researchers has used machine learning to produce a novel blood test that can predict a young person’s risk of developing a psychotic disorder, such as schizophrenia, years before the condition develops.

New research suggests a high-fat diet and antibiotics work together to promote a gut microbiome imbalance that can lead to bowel inflammation. The study sheds light on the causal mechanism by which environmental factors can trigger IBD.

Researchers looking for biomarkers to predict rheumatoid arthritis flare-ups have discovered a never-before-seen type of cell. Dubbed PRIME cells, they accumulate in the bloodstream seven days before a flare, but strangely disappear during the flare.

New research is uncovering how non-alcoholic fatty liver disease influences the neurological conditions associated with Alzheimer’s disease. The study describes how a protein produced in the liver can travel to the brain and trigger neuroinflammation.

One of the many deteriorative effects of aging in humans is a decline in immune system function. But scientists may have uncovered a way to reverse this trend by transplanting a type of white blood cell from the young into the old.

A new study has solved a long-standing mystery of how acute stress seems to amplify inflammatory disease, despite the fact many stress hormones actually suppress the immune system. It found a specific immune cell is released by fat cells when stressed.

Two new studies are offering strong evidence that bowel inflammation and obesity are risk factors for developing dementia. The studies are observational, and cannot determine causality, but they build on prior research reaching similar conclusions.

New data has found the cheap steroid dexamethasone significantly reduces deaths when administered to COVID-19 patients in intensive care. The treatment has been described as “the first major breakthrough in the therapeutics of COVID-19 infection”.