Inflammatory

More than one in 10 adults suffer from chronic rhinosinusitis, an inflammatory sinus condition. A new brain imaging study suggests the disease is linked with functional brain connectivity changes that could explain cognitive problems such as brain fog.

A study published in Nature Communications indicates a possible genetic association between stomach ulcers and depression. The research found a genetic link between a susceptibility for peptic ulcer disease and psychiatric disorders such as major depression.

Inflammatory bowel diseases, including ulcerative colitis and Crohn’s disease, are unpleasant, chronic conditions with few treatment options. Now, researchers may have found a way to potentially “switch on” the body’s natural tissue repair system.

Understanding what causes Crohn's disease could lead to new treatment targets, and scientists have just placed the crosshairs over a key enzyme they say acts as an "Achilles heel" for inflammation linked to the condition.

New research is describing the discovery of a novel subset of brain cell with the capacity to prevent neuroinflammation. This anti-inflammatory activity is modulated by molecules induced by gut bacteria revealing an exciting new gut-brain pathway.

Inflammation in the human body is a complex physiological response to a complex range of triggers, and scientists have just uncovered some useful new details about how it works by experimenting with muscles grown in the lab.

A new study describes one way immune cells become dysfunctional as we age, leading to the inflammatory hyperdrive that plays a role in most age-related disease from cancer to cognitive decline, and suggests this immune dysfunction can be reversed.

A first-of-its-kind study has found a link between COVID-19 severity and the gut microbiome. The research suggests specific microbial patterns correlate with disease severity and those bacterial imbalances may account for some cases of “long COVID”.

New research suggests e-cigarette vapor alone, free of nicotine or flavoring, can trigger gut inflammation. Across a series of experiments the study demonstrated how e-cigarette vapor can weaken the gut’s lining and lead to chronic inflammation.

Crohn’s disease is an inflammatory bowel condition triggered by an overactive immune system. Now researchers have developed a new kind of immunotherapy for Crohn’s that delivers a “triple punch” by tweaking the responses of different immune cells.

A brand new type of particle has been discovered in the human bloodstream. The sausage-shaped structures were first found by researchers at La Jolla Institute for Immunology in mice with sepsis, and they appear to be related to inflammatory disease.

Researchers have developed a drug that can mimic inflammation signals to lure stem cells to damaged tissue, without causing any further inflammation. The technique could be a boon for regenerative medicine to treat neurological disorders.