Karolinska Institutet

New research has found one in five people have a genetic mutation that confers greater resilience to cold temperatures. The study shows people with a deficiency generating a skeletal muscle protein shiver less and hold higher core temperatures in the cold.

Cancer cells are very energy-hungry, which could be a potential weakness. Now, researchers have developed an experimental drug that blocks mitochondrial metabolism, starving cancer cells of energy while leaving healthy cells relatively unscathed.

Exactly how exercise could be directly helping the body fight cancer has been unclear. Now, a study led by researchers from Sweden’s Karolinska Institutet has discovered the way exercise can bolster the cancer-killing ability of certain immune cells.

While much research has investigated short-term physiological responses to exercise a new study has set out to examine how long-term physical training, consistently performed for over a decade, can influence gene activity to prevent metabolic disease.

Scientists have discovered a new mechanism to help illustrate the rapid antidepressant qualities of ketamine. Imaging patients with depression revealed ketamine’s effects are a result of its interaction with a particular kind of serotonin receptor.

A genetic variant inherited from our ancient Neanderthal relatives and thought to confer heightened fertility has been found in modern humans. The new research suggests almost one in three European women carry some degree of the gene variant.

Four years after it was announced, the results of a controversial clinical trial have been published, finding a testosterone-reducing drug, originally developed for prostate cancer, lowered sexual interest in children for men with pedophilic disorder.

Scientists have thrown further weight behind the theory that Parkinson's could originate in the gut, with an investigation of the digestive system revealing possible tell-tale signs at the earliest stages of the disease.

Scientists have just discovered a new mechanism that can be key in regulating inflammation in sufferers of autoimmune disease, raising hopes of new drugs that can better protect against it and the ailments it can bring, such as rheumatoid arthritis.

A study, from Sweden’s Karolinska Institutet, has demonstrated a new method that can distinguish between two different, but closely related, strains of the herpes virus, offering evidence to suggest the virus plays a role in multiple sclerosis.

You may think that we’ve got a good handle on the organs in the body by now, but it turns out that the final count is surprisingly contentious. Researchers at Karolinska Institutet in Sweden claim to have discovered a new sensory organ in the skin that’s involved in pain detection and response.

A team of Swedish researchers have discovered three new types of neurons, which help carry auditory signals from the ear to the brain and may hold the secrets to treating hearing disorders like tinnitus.