Mount Sinai Hospital

A large international clinical trial has found combining three common heart disease drugs into the one pill is significantly more effective at preventing cardiovascular events and death compared to administering each of the medicines separately.

A study has homed in on a newly discovered mechanism that could prevent insulin resistance in type 2 diabetics. The research found disrupting the expression of a certain protein could protect beta cells and prevent patients from becoming insulin resistant.

Scientists may have unearthed a valuable new tool to study brain injuries, in the form of headbutting animals such as bighorn sheep and muskoxen, in which they've discovered hallmarks of head trauma for the very first time.

Depression is condition where deep brain stimulation is showing real promise, and a new study has uncovered fresh detail on how it induces anti-depressive effects, offering scientists a novel biomarker via which they can work to optimize the approach.

Researchers in the US have found changes to electrical activity in the heart can help predict which hospitalized COVID-19 patients are more likely to decline and die. The biomarker is easily measurable and may predict death several days in advance.

Surfing the wave of new research into medical uses for psychedelic compounds, the Icahn School of Medicine at Mount Sinai has launched a dedicated psychedelic center focusing on the study of MDMA and psilocybin for PTSD and other stress-related conditions.

A new study has identified three different molecular subtypes of Alzheimer's disease. The research suggests these subtypes are so distinct from one another they could account for previous clinical trial failures and inconsistent translational studies.

A study is the first to report successful results of a Phase 1 trial testing a novel universal flu vaccine. The trial found the experimental vaccine to be both safe and effective at generating a long-term immune response in a small number of adults.

A phase 2 clinical trial of a cholesterol-reducing drug called evinacumab has reported promising results. In patients with extremely high cholesterol, the drug was able to reduce levels by about half, compared to a placebo.

A new study is suggesting signs of the disease ALS may be detectable in teeth, decades before the onset of any symptoms. The research points to a dysfunction in metabolizing metals as a possible factor in the onset of this still mysterious disease.

The Mount Sinai Kyabirwa Surgical Facility is a superb project in Uganda that provides locals with access to much-needed surgical treatment. The facility makes good use of off-grid technology, including solar panels and rainwater collection systems.

New research reveals different types of fasting results in significantly different immune responses.