Yale

Scientists at Yale University have uncovered an overlooked mechanism that may be behind the symptoms of Alzheimer’s disease. The team points the finger at small swellings on axons near plaques that build up in the brain, suggesting new drug targets.

The US Food and Drug Administration (FDA) has approved the first drug that can delay the onset of type 1 diabetes. A recent trial has shown that the drug, named teplizumab, can give patients several extra disease-free years.

Researchers have demonstrated a new technique to fight cancer by attaching immunotherapy drugs to a molecule that seeks out the acidic environment of cancer cells. In tests in mice, a single dose was enough to eradicate even advanced tumors.

A team at Yale University has claimed a breakthrough in the study of the human genome with a technology they liken to "spray paint" for cells, which they've now demonstrated by mapping previously unknown proteins for the first time.

Dinosaurs sit at the crossroads between reptiles and birds, leading scientists to debate whether they were warm- or cold-blooded. A new study may have the answer for different dinosaurs by analyzing metabolic markers from their breath in their bones.

Researchers have homed in on strains of gut bacteria associated with the severity of a common form of stroke. The findings build on research suggesting future therapies targeting the microbiome could reduce a person’s risk, and aid in recovery.

New research has found the world’s first portable MRI machine can accurately detect ischemic strokes. The machine was authorized by the FDA in 2020 and researchers are increasingly demonstrating it to be as effective a tool as bigger MRI devices.

By studying the behavior of a protein tightly linked with a wide range of cancers, scientists have uncovered the role it plays in regulating body weight, deepening our understanding of the way our bodies respond to food.

Promising research raises the possibility of treating diabetes without drugs. Across three animal models researchers have demonstrated how bursts of ultrasound targeted at specific clusters of nerves in the liver can lower insulin and glucose levels.

In pursuit of a treatment for alopecia areata, an autoimmune disorder that causes hair loss, scientists have found new success by repurposing a common arthritis drug which proved effective in around a third of subjects.

A study investigating the health effects of long-term calorie restricted diets in humans has homed in on a protein that seems to play a key role in age-related immune dysfunction, and the researchers hypothesize it could be targeted to extend lifespan.

Engineers from Yale University have developed a wearable device that can help individuals assess whether they have been exposed to SARS-CoV-2. The device clips onto a person’s clothes and capture aerosolized viral particles in the surrounding environment.