Immunotherapy

Researchers have developed a liquid gel that solidifies when injected into a solid tumor, is visible on a CT scan, and can slow-release cancer-fighting treatments. Combining the gel with immunotherapy improved survival in treatment-resistant cancers.

Immunotherapy is a promising cancer treatment, but it can take too long. In a new study, scientists have taken steps towards an “off-the-shelf” therapy that could be mass produced and quickly rolled out to patients with a variety of cancer types.

Cancer vaccines are a medical holy grail – but what if you could repurpose a vaccine you’ve already had? Scientists have demonstrated in mice a way to trick the immune system into attacking tumors by mistaking them for a pathogen it already targets.

Researchers have found that administering under-the-tongue immunotherapy given to young peanut-allergic children is a safe and effective way of desensitizing them to the food. It may provide another method of curbing this potentially deadly allergy.

Each year, more than 150,000 Americans are diagnosed with bowel cancer, or colorectal cancer, and the disease has a dire survival rate if surgery isn’t successful. Scientists now believe they have found one tiny molecule that could change all that.

Around 1.6 million Americans live with inflammatory bowel disease, dealing with persistent and debilitating relapses. Scientists have identified how a specialized subset of T cells falter in flare-ups, and they may hold they key to long-term recovery.

Scientists have discovered an unknown type of immune cell in people who've successfully beat cancer. These home in on multiple targets at once, preventing new tumors forming for up to a year later and could lead to more effective cancer therapies.

A phase 1 clinical trial exploring the use of fecal transplants to supplement immunotherapy treatment for melanoma has found it to be safe and has the potential to improve patients’ response to treatment.

New research has discovered that a fundamental nutrient found in cells is key to maintaining the body’s cancer-destroying immune response. The discovery may lead to more effective ways of treating the disease.

A chemo and immunotherapy combo has proven promising in treating patients with advanced Hodgkin Lymphoma, and removes the need for radiation therapy in kids. In a clinical trial, 94% of patients receiving the combo treatment entered remission.

A Phase 3 clinical trial of the drug donanemab has shown it can significantly slow cognitive and functional decline in people with early-stage Alzheimer’s disease, compared with existing treatments.

Constantly fighting cancer or other diseases can exhaust our immune system’s T cells. A new study has identified a way of reviving exhausted T cells so they’re ready to fight again, improving the effectiveness of cancer immunotherapy.