Low-density lipoprotein (LDL) cholesterol

A new gene therapy lowered two heart disease-related lipids in a human clinical trial

Medical Innovations

One-off lipid-lowering gene therapy a success in world-first human trial

In a world-first trial, scientists used a one-off CRISPR gene edit to switch off a liver “fat brake” gene, slashing stubborn LDL cholesterol and triglycerides in patients whose levels refused to budge on standard treatments.

Eggs have long been caught up in a nutritional moral panic

Diet & Nutrition

Landmark study flips decades of cholesterol panic aimed at eggs

A world-first clinical trial has revealed that eggs can lower LDL cholesterol, with overall diet saturated fat is taken into account. It rewrites the narrative on dietary cholesterol and offers a science-backed redemption arc to a nutritional villain.

Combining new and old drugs halved levels of "bad" cholesterol

Heart Disease

New & old drug combo drops cholesterol by 49% in human trial

Some people can’t get their bad cholesterol levels down, even if they take cholesterol-lowering meds. A clinical trial using a combination of existing and not-yet-released cholesterol tablets lowered bad cholesterol by almost half.