Tumors
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Scientists in Spain have uncovered a mechanism behind why some cancer patients don’t respond well to treatments – and more importantly, found a “weak spot” that could be targeted by existing drugs.
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Researchers have found that adding a booster protein can significantly improve the outcome of cancer immunotherapy. Tests in mice showed the protein produced 10,000 times more cancer-targeting immune cells, with all mice surviving the experiment.
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A study has analyzed the genomes of cancer cells from 12,000 patients identifying 58 new mutational signatures that offer clues to novel causes of cancer. The findings offer a whole trove of new resources to guide future studies on cancer treatments.
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Analysis of an ongoing project that has been tracking the health of nearly one million women in the UK for more than 20 years has found no association between increased risk of brain tumors and cell phone use.
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Heightened tissue growth can result when cells come under tension, and a new study on cancer cells has pinpointed the biological mechanism that drives this process, which the authors believe can be targeted to prevent tumor development.
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New preclinical work has found a combination of three experimental immunotherapy drugs could help shrink pancreatic tumors. Each of the drugs have demonstrated safety in early human trials and the hope is to begin testing the triple combo by the end 2021.
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Radiotherapy is one of the best treatments we have against cancer, but there's room for improvement. Now, researchers in Japan have developed nanoparticles that can penetrate tumors and kill them from within, after being activated by external X-rays.
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The earlier cancer is detected, the better. MIT scientists have developed a diagnostic system that can be performed as a urine test to detect the presence of cancer, and if a positive is returned, a follow-up test can locate where it is in the body.
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Cancer becomes far more dangerous when it spreads through the body, known as metastasis. A newly identified protein stops cells getting into the bloodstream – and tumor cells can ignore it, which may reveal a new drug target for cancer treatment.
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Researchers at Karolinska Institute in Sweden have made a breakthrough in the arms race that is cancer immunotherapy. The team has blocked a protein that silences an important tumor-suppressing protein, allowing the latter to get back to work.
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Immunotherapy is a promising avenue for cancer treatment, but it has trouble against solid tumors without triggering major side effects. Now, researchers have developed a new form of the treatment that supercharges a different type of immune cell.
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Researchers at the Chinese Academy of Sciences have developed an intriguing new way to fight cancer by combining two types of experimental therapies. Their secret ingredient is creating a feedback loop using modified blood platelets.
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