Drugs
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High cholesterol levels are a common and potentially deadly health problem, but a new drug could help more people manage the condition. An experimental pill has been shown to reduce levels of “bad” cholesterol by 60% in a phase 2 clinical trial.
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Scientists have developed a new technique that could eventually lead to new potential treatments for Alzheimer’s disease. The team investigated a compound that breaks down a protein associated with the disease, with tests in mice improving symptoms.
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Scientists have discovered how a specific brain circuit functions during fentanyl withdrawal, potentially leading to relapse. Suppression of this could lead to better, targeted medical treatments for opioid use disorders.
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While breathalyzers make it quick and easy to tell if someone is drunk, it takes more time and effort to determine if they're intoxicated by drugs such as cannabis. A new device known as Gaize could reportedly soon change that.
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Male contraceptives have traditionally been limited to condoms and vasectomies. Now scientists have demonstrated a promising new method that takes the form of a pill that can be taken just before sex, greatly reducing fertility for 24 hours.
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ALS is a debilitating neurodegenerative disease with poor outcomes, but a pair of new studies may point towards a more optimistic future. In tests in human cells and live mice, scientists identified promising new targets for potential treatment.
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For half a century beta blockers have been used to help patients with cardiovascular problems manage their abnormal heart rhythms, but a new study tracking over a million people has found the common drug may also reduce aggression and violent behavior.
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Scientists at MIT have developed bottlebrush-shaped molecules that can carry groups of different cancer drugs in just the right ratios. Tests in mice showed significantly improved outcomes compared to just giving the drugs loose.
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Researchers have discovered an old class of antipsychotic drugs may offer clues to a novel kind of treatment for type 2 diabetes. While the drugs may be directly repurposed, they could also be slightly modified to specifically target blood sugar control.
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In an ideal world, managing diabetes wouldn’t involve insulin injections but just popping a pill. Now a team of scientists has demonstrated an oral tablet that’s self-propelled by chemical “micromotors” to deliver insulin in the colon of rats.
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The FDA has approved a new drug for patients in the early-stages of Alzheimer's disease but growing concerns over its safety and real-world efficacy have led to division amongst researchers, with some suggesting it should not be authorized for wide use.
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Researchers in Japan have demonstrated a promising new cancer treatment. The team developed artificial DNA sequences shaped like hairpins that latch onto molecules overexpressed in cancer and trigger a strong immune response.
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